| Background. Exercise has been recognized to improve functional limitation and pain in knee osteoarthritis (OA). However, exercise has also been reported to induce exercise-related knee pain. This study aimed to compare the effect of Tai Chi and jogging on knee pain in healthy and related factors. Material and methods. This cross-sectional study involved male and female 180 participants aged 40-60-years. The participant consisted of Tai Chi (n=60), jogging (n= 60), and sedentary (n=60) as control. Weight height and body mass index (BMI) were measured. The pain was evaluated using The Western Ontario and McMaster Uni versi - ties Osteoarthritis Index (WOMAC). Risk factors of knee OA were included. ANOVA followed with post hoc test, Chi-square, Pearson and Spearman correlation, and logistic regression were applied to compute statistical analysis tests. Results. There are 4 participants (2.5%) with the WOMAC score index at high risk of knee OA. Seventy-six participants (63%) engaged in Tai Chi and jogging had knee pain. The possible risk factors of knee pain, which significantly correlated with knee pain were age, weight, BMI, family history of rheumatoid arthritis, and spine align ment. A line - ar regression indicated both Tai Chi and jogging did not significant different compared to control (OR 1.23, CI 95% 0.59-2.25, p=0.58 and OR 0.69, CI 95% 0.32-1.47, p=0.34, respectively). Conclusion. The incidence of knee pain in Tai Chi and jogging is quite high. However, the WOMAC score index is mostly normal. Tai Chi tends to aggravate knee pain than jogging in people with risk factors. |