Phenotypic Profiles of Language-Impaired Children Based on Genetic/Family History.  

Oleh:

Curtiss, Susan ; Tallal, Paula ; Wulfeck, Beverly ; Townsend, Jeanne

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Brain and Language (Full Text) vol. 41 no. 1 (Jul. 1991), page 81-95.

Ketersediaan

Perpustakaan PKBB Nomor Panggil: 405/BAL/41 Non-tandon: tidak ada Tandon: 1

Lihat Detail Induk

Isi artikel

Although etiological influences in developmental language impairment (dysphasia) are not well defined, a significant increase of family aggregation for the disorder has been reported. We report data from a large cohort of language impaired (L1) children participating in the San Diego longitudinal study in which we examined whether children with or without positive family histories show different phenotypic profiles. bue to the longitudinal design of the study, questions pertaining to change over time are also addressed. Second, a subgroup of the most impaired children were reevaluated to obtain additional information pertaining to family history and phenotypic outcome. Approximately 70% of the LI children met criteria for inclusion as family history positive, with fathers reporting a history of language or learning problems one and a half to two times as frequently as mothers. L1 children with or without a positive family history were not sig

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