Splenic Calcification  

Oleh:

Dasanu, Constantin A. ; Codreanu, Ion

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 365 no. 11 (Sep. 2011), page 1042.
Topik: Avascular Necrosis; Sickle Cell Disease
Fulltext: Splenic Calcification.pdf (103.64KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2011.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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A 28-year-old woman with sickle cell disease who had previously undergone surgery for avascular necrosis of the left humeral head presented to the emergency department with a 1-month history of intermittent pain in the right shoulder. On the basis of imaging studies, avascular necrosis of the right humeral head was diagnosed. In the course of the investigations, evidence of a densely calcified spleen was noted on plain radiography (Panel A, upright view, arrows), on bone scintigraphy with technetium-99m–labeled methylene diphosphonate (Panel B, posterior view, arrow), and on contrast-enhanced computed tomography (Panel C, coronal view, arrows; and Panel D, sagittal view, arrow). A young child with sickle cell disease typically has a large, dysfunctional spleen. Repeated attacks of vaso-occlusion and infarction eventually result in the small, fibrotic, nonfunctional spleen, with occasional calcification, that is a hallmark of sickle cell disease in adults. Various patterns of splenic calcification have been described in such patients. The care of this patient was managed conservatively by prescribing opiate analgesics and ensuring that her vaccinations against encapsulated organisms were current.

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