Pengembangan dan Validasi Metode Kromatografi Cair Kinerja Tinggi (KCKT) Fase Terbalik pada Analisis Multikomponen Parasetamol, Propifenazon dan Kafein  

Oleh:

Patramurti, Christine

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: SIGMA: Jurnal Sains dan teknologi vol. 13 no. 2 (Jul. 2010), page 179-186.
Topik: Paracetamol; Propifenazon; Caffeine; HPLC; Validity

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: SS25 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Paracetamol, propifenazon and caffeine are active ingredients that are usually founded in analgesic-antipyretics medicine. These compounds are soluble in ethanol and can absorb at ultra violet wavelength. High Performance Liquid Chromatography (HPLC) is the method that can be used to qualitative and quantitative multicomponent analysis. The instrumentation of HPLC consists of Zorbax ODS colom (4,6mm x 25cm); mobile phase methanol: aquabidest (40 : 60) at the flow rate of 2ml/minute and UV detector at 272 nm. The HPLC method meet the validation criteria, i.e: linearity, specificity, accuration and pressision parameter.

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