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Case 39-2010 — A 19-Year-Old Woman with Nausea, Jaundice, and Pruritus
Oleh:
Friedman, Lawrence S.
;
Gee, Michael S.
;
Misdraji, Joseph
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
The New England Journal of Medicine (keterangan: ada di Proquest) vol. 363 no. 26 (Dec. 2010)
,
page 2548-2557.
Topik:
Malaise
;
Vomiting
;
Upper Respiratory Symptoms
Ketersediaan
Perpustakaan FK
Nomor Panggil:
N08.K.2010.01
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Presentation of Case Dr. Kerry L. Massman (Medicine): A 19-year-old woman was transferred to this hospital because of nausea, jaundice, and pruritus. The patient had been well until approximately 2.5 weeks earlier, when malaise, vomiting, and upper respiratory symptoms developed, which resolved after 3 days. Approximately 1 week before admission, pruritus and dark urine developed. She noted darkening of her skin, which she attributed to sun exposure. Three days later, for a headache, she reportedly took three doses of oxycodone–acetaminophen that she received from a friend, pseudoephedrine, and tablets containing a combination of acetaminophen, aspirin, and caffeine. Three days before admission, her mother brought her to the emergency department at another hospital because of increasing discoloration of her eyes and skin. She reported generalized malaise, decreased appetite, and a weight loss of approximately 3 kg during the previous month. She did not have diarrhea or abdominal pain. On examination, the vital signs were normal, and the conjunctivae and skin were icteric; the remainder of the examination was normal. Results of a complete blood count, a differential count, and renal-function tests were normal, as were plasma levels of electrolytes, glucose, calcium, alkaline phosphatase, and albumin. The total protein level was 8.2 g per deciliter (reference range, 6.0 to 8.0); other results are shown in Table 1Table 1 Laboratory Data.. The patient was advised to avoid alcohol and over-the-counter medications, and she was discharged with a follow-up appointment at a medical clinic 2 days later.
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