The effect of coffee on blood pressure and cardiovascular disease in hypertensive individuals: a systematic review and meta-analysis  

Oleh:

Mesas, Arthur Eumann ; Leon-Munoz, Luz M ; Rodriguez-Artalejo, Fernando ; Lopez-Garcia, Esther

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The American Journal of Clinical Nutrition vol. 94 no. 04 (Oct. 2011), page 1113-1126 .
Topik: PUBLIC HEALTH; Nutritional Epidemiology; Coffee and Caffeine; Cardiovascular Disease; Hypertensive Persons

Ketersediaan

Perpustakaan FK Nomor Panggil: A07.K.2011.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Background: The effect of coffee and caffeine on blood pressure (BP) and cardiovascular disease (CVD) in hypertensive persons is uncertain. Objective: The objective was to summarize the evidence on the acute and longer-term effects of caffeine and coffee intake on BP and on the association between habitual coffee consumption and risk of CVD in hypertensive individuals. Design: A systematic review and meta-analysis of publications identified in a PubMed and EMBASE search up to 30 April 2011 was undertaken. Data were extracted from controlled trials on the effect of caffeine or coffee intake on BP change and from cohort studies on the association between habitual coffee consumption and CVD. Results: In 5 trials, the administration of 200–300 mg caffeine produced a mean increase of 8.1 mm Hg (95% CI: 5.7, 10.6 mm Hg) in systolic BP and of 5.7 mm Hg (95% CI: 4.1, 7.4 mm Hg) in diastolic BP. The increase in BP was observed in the first hour after caffeine intake and lasted =3 h. In 3 studies of the longer-term effect (2 wk) of coffee, no increase in BP was observed after coffee was compared with a caffeine-free diet or was compared with decaffeinated coffee. Last, 7 cohort studies found no evidence of an association between habitual coffee consumption and a higher risk of CVD. Conclusions: In hypertensive individuals, caffeine intake produces an acute increase in BP for =3 h. However, current evidence does not support an association between longer-term coffee consumption and increased BP or between habitual coffee consumption and an increased risk of CVD in hypertensive subjects.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali