The Effects of Allostatic Load on Neural Systems Subserving Motivation, Mood Regulation, and Social Affiliation  

Oleh:

Beauchaine, Theodore P. ; Neuhaus, Emily ; Crowell, Sheila E. ; Zalewski, Maureen ; Potapova, Natalia

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Development and Psychopathology vol. 23 no. 4 (Nov. 2011), page 975-999.
Topik: Allostasis; Developmental Psychopathology; Stress; Allostatic Load; Personality
Fulltext: The Effects of Allostatic Load on Neural Systems Subserving Motivation, Mood Regulation, and Social Affiliation.pdf (278.79KB)

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: DD21.21 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

The term allostasis, which is defined as stability through change, has been invoked repeatedly by developmental psychopathologists to describe long-lasting and in some cases permanent functional alterations in limbic-hypothalamic-pituitary-adrenal axis responding following recurrent and/or prolonged exposure to stress. Increasingly, allostatic load models have also been invoked to describe psychological sequelae of abuse, neglect, and other forms of maltreatment. In contrast, neural adaptations to stress, including those incurred by monoamine systems implicated in (a) mood and emotion regulation, (b) behavioral approach, and (c) social affiliation and attachment, are usually not included in models of allostasis. Rather, structural and functional alterations in these systems, which are exquisitely sensitive to prolonged stress exposure, are usually explained as stress mediators, neural plasticity, and/or programming effects. Considering these mechanisms as distinct from allostasis is somewhat artificial given overlapping functions and intricate coregulation of monoamines and the limbic-hypothalamic-pituitary-adrenal axis. It also fractionates literatures that should be mutually informative. In this article, we describe structural and functional alterations in serotonergic, dopaminergic, and noradrenergic neural systems following both acute and prolonged exposure to stress. Through increases in behavioral impulsivity, trait anxiety, mood and emotion dysregulation, and asociality, alterations in monoamine functioning have profound effects on personality, attachment relationships, and the emergence of psychopathology.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali