Something to Celebrate; Arthritis and Botolinum Toxin  

Oleh:

[s.n]

Jenis: Article from Bulletin/Magazine
Dalam koleksi: The Economist (http://search.proquest.com/) vol. 401 no. 8763 (Dec. 2011), page 79.
Topik: Research & Development--R&D; Pharmaceutical Industry; Arthritis; Toxins; Anti Inflation
Fulltext: Arthritis and Botulinum Toxin.pdf (40.54KB)

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: EE29.69 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Arthritis is the bane of millions of lives. Though it comes in many forms, their common theme is inflammation of the tissues around a joint in the skeleton. Treatment is merely palliative: anti-inflammatory drugs, painkillers or both. But a piece of research published this week in Biochemistry, by Edwin Chapman of the University of Wisconsin and his colleagues, offers arthritis sufferers hope from a strange quarter: botulinum toxin. The toxin molecules attach themselves to a protein called synaptotagmin, which is found on the surface membranes of nerve cells at their junctions with muscle cells. Thence they are ingested into the cell, where they disable another protein, SNAP-25, the role of which is to help release a chemical messenger called acetylcholine. The first stage works. The toxin/antibody complex successfully gloms onto the macrophages. The toxin does get inside them. And the cells do stop signalling. It is a long way from there to a treatment.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali