Combined oral contraceptives in women with menstrual migraine without aura  

Oleh:

De Leo, Vincenzo ; Scolaro, Valeria ; Musacchio, Maria Concetta ; Di Sabatino, Alessandra

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 96 no. 04 (Okt. 2011), halaman 917-920.
Topik: Contraception; drospirenone; headache; hormone-free interval; migraine without aura

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2011.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To compare the efficacy of two regimens (21 active pills + 7 placebo pills vs. 24 active pills + 4 placebo pills) of combined oral contraception (COC), both containing 20 µg of ethinyl E2 and 3 mg of drospirenone, in improving the severity of pure menstrual migraine without aura. Design Prospective randomized study. Setting Patients attending the gynecology department of the University of Siena for consultation regarding an appropriate contraception. Patient(s) Women ages 20 to 35 years (n = 60) suffering from pure menstrual migraine without aura. Intervention(s) Three months of contraceptive use (ethinyl E2 20 µg/drospirenone 3 mg) in two different regimens: group A received 21 active + 7 placebo pills whereas group B received 24 active + 4 placebo pills. Main Outcome Measure(s) Monthly evaluation of the duration and severity of patients’ daily headache attacks. Result(s) Although both study groups demonstrated significant reduction in the intensity and duration of menstrual migraine, patients in group B (24/4 COC) reported a significant reduction in the intensity and a shorter duration of their menstrual migraine, compared with group A (21/7 COC). Conclusion(s) The 24/4 COC regimen is recommended as the preferred treatment for patients suffering from pure menstrual migraine without aura.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali