Stress and Adaptation : Toward Ecologically Relevant Animal Models  

Oleh:

Koolhaas, Jaap M. ; Boer, Sietse F. de ; Buwalda, Bauke

Jenis: Article from Journal - e-Journal
Dalam koleksi: Current Directions in Psychological Science vol. 15 no. 03 (Jun. 2006), page 109-112.
Topik: stress; adaptation; animal models; biology; behavior
Fulltext: 03. Stress and Adaptation - Toward Ecologically Relevant Animal Models.pdf (91.88KB)

Isi artikel

Animal models have contributed considerably to the current understanding of mechanisms underlying the role of stress in health and disease. Despite the progress made already, much more can be made by more carefully exploiting animals’ and humans’shared biology, using ecologically relevant models. This allows a fundamental analysis of factors modulating individual adaptive capacity and hence individual vulnerability to disease. This article highlights an emerging scientific approach that uses a framework of interpretation that is more biologically oriented than previous approaches, to evaluate both the adaptive and maladaptive nature of the stress response in relation to existing environmental demands.

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