Molecular Genetic Studies of Eating Disorders : Current Status and Future Directions  

Oleh:

Klump, Kelly L ; Culbert, Kristen M.

Jenis: Article from Journal - e-Journal
Dalam koleksi: Current Directions in Psychological Science vol. 16 no. 01 (Feb. 2007), page 37-41.
Topik: Anorexia Nervosa; Bulimia Nervosa; Genetic; Gene
Fulltext: 08. Molecular Genetic Studies of Eating Disorders - Current Status and Future Directions.pdf (102.52KB)

Isi artikel

We review association studies that have examined the genetic basis of eating disorders. Overall, findings suggest that serotonin, brain-derived neurotrophic factor, and estrogen genes may be important for the development of the disorders. These neuronal systems influence behavioral and personality characteristics (e.g., anxiety, food intake) that are disrupted in eating disorders. Future studies would benefit from larger sample sizes and inclusion of behavioral and personality covariates in analyses. Consideration of the mechanisms of genetic effects and interactions between genes and environment is also needed to extend conceptualizations of the genetic basis of these disorders.

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