Corticotropin-Releasing Factor and the Psychobiology of Early-Life Stress  

Oleh:

Gillespie, Charles F. ; Nemeroff, Charles B.

Jenis: Article from Journal - e-Journal
Dalam koleksi: Current Directions in Psychological Science vol. 16 no. 02 (Apr. 2007), page 85-89.
Topik: Trauma; Neglect; Depression; Stress; Corticotropin- Releasing Factor
Fulltext: 07. Corticotropin-Releasing Factor and the Psychobiology of Early-Life Stress.pdf (105.86KB)

Isi artikel

Trauma and neglect during childhood are increasingly appreciated as factors in the etiology of adult mood and anxiety disorders. Much has been learned about the role of stress biology in the persisting effects of early adverse experience on adult psychopathology. Here we present an overview of developmental trauma in the psychobiology of depression and anxiety. We emphasize the role of corticotropin-releasing factor in the pathophysiology of these disorders, focusing on the transduction of early life trauma into adult psychopathology.

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