Induction of apoptotic cell death via accumulation of autophagosomes in rat granulosa cells  

Oleh:

Jong, Yeob Choi ; Min, Wha Jo ; Eun, Young Lee

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 95 no. 04 (Mar. 2011), page 1482-1486.
Topik: Apoptosis; autophagy; bcl-2; caspases; granulosa cell

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2011.03 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

This study evaluated the effect of autophagosome accumulation on apoptotic cell death in granulosa cells from developing follicles. Our results indicate that the accumulation of autophagosomes induces apoptotic cell death of granulosa cells through decreased bcl-2 expression and subsequent caspase activation.

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