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Hubungan Trombosit dan Laju Endap Darah Terhadap Derajat Keparahan Pasien Tuberkulosis Paru Sebelum dan Sesudah Pengobatan Intensif di Rumah Sakit Atma Jaya
Bibliografi
Author:
EKAPUTRI, MARIA VANIA TRI
;
Sahiratmadja, Edhyana Kusumastuti
(Advisor);
Chriestya, Febie
(Advisor);
Simon, Sumanto
(Examiner)
Topik:
TUBERCULOSIS
;
Erythrocyte sedimentation rate
;
inflammation
;
intensive therapy
;
platelet
;
severity of disease
;
tuberculosis
;
Derajat keparahan
;
inflamasi
;
laju endap darah
;
terapi intensif
;
tuberkulosis
;
trombosit
Bahasa:
(ID )
Penerbit:
Fakultas Kedokteran Unika Atma Jaya
Tempat Terbit:
Jakarta Utara
Tahun Terbit:
2018
Jenis:
Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Fulltext:
KTI MARIA VANIA TRI EKAPUTRI (2014060091).pdf
(2.36MB;
29 download
)
Ketersediaan
Perpustakaan FK
Nomor Panggil:
KTI-FK- 1382
Non-tandon:
tidak ada
Tandon:
1
Lihat Detail Induk
Abstract
Background. Indonesia is the third country with the largest TB cases in the world. Efforts are needed to monitor TB therapy. Platelets and ESRs are associated with an inflammatory response in some diseases, as well as pulmonary TB and are thought to be a prognostic factor of success and an intensive therapy response.
Objective. Knowledge of the relationship of platelets and ESR to the degree of severity of pulmonary TB patients before and after intensive treatment at Atma Jaya Hospital.
Methods. Data taken from the medical records of pulmonary TB patients at Atma Jaya Hospital period 2016-2017. The data taken were weight, platelet level, ESR, and sputum smear examination before and after intensive therapy. The distribution test was performed using Kolmogorov-Smirnov test. Data analysis with paired T test and general linear model.
Results. In 53 patients with pulmonary TB with the most male sex (54.7%), age group 15-25 years (24.5%), and mean age 41 years. There was a significant decrease (p <0.05) between platelet and ESR levels after intensive treatment. There was no significant difference between platelet and ESR levels before and after intensive treatment of TB severity based on sputum smear conversion (p> 0.05). There was a significant difference between platelet level before and after intensive treatment of TB severity based on weight change> 5% (p <0.05), but not significant on ESR (p> 0.05).
Conclusion. Reduced platelets and ESRs after intensive treatment can be a marker of therapeutic response. Platelets and ESRs can be a marker of intensive therapeutic response.
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