Introduction. Olfactory deficit is a degenerative process and pre-clinic indication of Alzheimer’s Disease, so it is very important to understand about the risk factor and
ApoE4 role toward the olfactory deficit in elderly.
Method. Using research analytics study with cross sectional approach. Total of the research subject is 158 elderly with age above 60. This research carry out respondent characteristics analysis (age, education level, gender), olfactory system examination, and ApoE4. Data analysis using the Chi-Square test with 95% Confidence Interval (?? = 0.05).
Result. Highest percentage of subject in women under the age of 70, educated above 6 years, result shows that almost one-third (1/3) has ApoE4 (+) genotype and almost half of the population has olfactory system deficit. There is a meaningful relation between age with olfactory system (P=0.002), as well there is a meaningful relation
between education level with olfactory system (P=0.001). However, there is no meaningful relation between gender (P=0.117) and ApoE4 (P=0.128) to olfactory system.
Discussion. Olfactory system score in elderly with age above 70 with low education level is lower, despite not affected by gender and Apolipoprotein E. Researcher
suggest furthermore the age cut-off to start screening for olfactory deficit can be discover. |