Endocrine gland–derived vascular endothelial growth factor concentrations in follicular fluid and serum may predict ovarian hyperstimulation syndrome in women undergoing controlled ovarian hyperstimulation  

Oleh:

Min-Zhi, Gao ; Xiao-Ming, Zhao ; Zhao-Gui, Sun ; Yan, Hong ; Lei-Wen, Zhao ; Hui-Qin, Zhang

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 95 no. 02 (Feb. 2011), page 673-678.
Topik: OVARY; Endocrine gland–derived vascular endothelial growth factor; vascular endothelial growth factor; ovarian hyperstimulation syndrome; controlled ovarian hyperstimulation; ovarian response

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2011.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To assess the predictive value of endocrine gland–derived vascular endothelial growth factor (EG-VEGF) concentrations in follicular fluid (FF) and serum for ovarian hyperstimulation syndrome (OHSS) in patients undergoing controlled ovarian hyperstimulation. Design Retrospective, case-control study. Setting University hospital, IVF center. Patient(s) Seventeen women with OHSS and 61 controls. Intervention(s) None. Main Outcome Measure(s) FF and serum EG-VEGF and VEGF concentrations, IVF outcome. Result(s) FF and serum EG-VEGF concentrations showed a significant negative correlation with serum E2 concentration on the day of hCG administration. FF, but not serum, VEGF concentrations also showed a significant negative correlation with serum E2 concentrations on hCG day. The FF EG-VEGF, FF VEGF, and serum EG-VEFG concentrations were significantly lower in the OHSS group than in the non-OHSS group. There was no significant difference in serum VEGF concentrations. Among FF and serum EG-VEGF and VEGF concentrations, only FF EG-VEGF concentrations were significantly lower in patients with moderate OHSS than in those with mild OHSS. Conclusion(s) FF and serum EG-VEGF concentrations may predict OHSS occurrence. Furthermore, FF EG-VEGF concentrations were significantly correlated with OHSS severity; thus, EG-VEGF appears to be more valuable than VEGF for predicting OHSS.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali