Background: Diabetes is one of the world health issues. Cases of death caused by diabetes in Indonesia in 2015 are around 184.985 with a prevalence of 6.2% from about 10 million people had diabetes. Traditional therapy becomes one of the alternatives in the treatment of diabetes. Kefir is a fermented milk that can be made from cow and goat's milk. It was stated in the previous studies, the glucose level in the blood can be reduced by consuming kefir.
Methods: This study was in vivo experiment. This study was conducted over 30 days using 28 alloxan induced Wistar rats. The rats were divided into 4 groups with each consisting of 7 rats. Blood glucose level were measured by glucometer and measured before induction, 3 days, 7 days, 14 days, 21 days, and 30 days after induction.
Results: The treatment with metformin, cow’s milk kefir, and goat’s milk kefir showed a significant reduction in blood glucose levels (p <0.005). The blood glucose level reduced by metformin was 247,43 mg/dL, by cow’s milk kefir was 230,29 mg/dL, and by goat’s milk kefir was 230,29 mg/dL. In Post Hoc Bonferroni test it can be seen that p> 0.005 meaning there is no significant difference between groups.
Conclusion: There was a significant decrease in blood sugar levels in the consumed of cow’s milk kefir and goat’s milk kefir but there was no significant difference in cow’s milk kefir and goat’s milk kefir in lowering blood sugar levels. |