Magnetic resonance elastography of uterine leiomyomas: a feasibility study  

Oleh:

Stewart, Elizabeth A. ; Taran, F. Andrei ; Jun, Chen ; Gostout, Bobbie S. ; Woodrum, David A.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 95 no. 01 (Jan. 2011), page 281-284 .
Topik: Leiomyomas; magnetic resonance; elasticity; uterus; feasibility studies; elasticity imaging techniques/methods; adult; humans; female

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2011.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To determine the feasibility of performing in vivo magnetic resonance elastography (MRE) for uterine leiomyoma. Design Pilot study. Setting Academic medical center. Patient(s) Six subjects planning surgical excision of uterine leiomyomas. Intervention(s) MRE before planned surgery. Main Outcome Measure(s) Achieving an appropriate phase signal–to-noise ratio (PSNR) in the leiomyoma to allow assessment of leiomyoma elasticity in kilopascals (kPa). Result(s) MRE was successful in all subjects for uteri ranging from 100 to >1,000 g. Subjects had body mass indexes ranging from 23.0 to 38.0 kg/m2. Appropriate PSNRs, ranging from 5.45 to 42.28, were achieved for leiomyomas in all subjects. Mean elasticity of uterine leiomyomas ranged from 3.95 to 6.68 kPa. Conclusion(s) MRE is a feasible technique for studying the in vivo mechanical properties of uterine leiomyomas and demonstrates significant heterogeneity in elasticity between lesions. Further work is necessary to optimize the technique and understand the clinical utility of this technique for women with uterine leiomyomas.

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