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BukuPerbandingan Pola Kepekaan Bakteri Staphylococcus epidermidis dari Sampel Klinis dan Lingkungan RS Atma Jaya Tahun 2014-2017
Bibliografi
Author: HARTONO, BRYAN ARISTA ; Narwati, Benedicta Yulia Tanti (Advisor); Tjoa, Enty (Advisor); Angelina, Yohanna (Examiner)
Topik: ANTIMICROBIAL; Antimicrobial susceptibility test; Staphylococcus epidermidis; Resistance profile; Uji kepekaan antimikroba; Profil resistensi
Bahasa: (ID )    
Penerbit: Fakultas Kedokteran Unika Atma Jaya     Tempat Terbit: Jakarta Utara    Tahun Terbit: 2017    
Jenis: Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Fulltext: KTI Bryan Arista Hartono.pdf (2.87MB; 12 download)
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: KTI-FK-1267
    • Non-tandon: tidak ada
    • Tandon: 1
 Lihat Detail Induk
Abstract
BACKGROUND: Health-care Associated Infections (HAIs) accidental rate are 15% in development countries, reported by M. coultier1, in 2011. Staphylococcus epidermidis (S. epidermidis) is one of the bacteria that risk to cause HAIs and mostly isolated in clinical samples, in Atma Jaya Hospital, in 2014-2017. The bacteria normally found in human skins and mostly located in environment. Charactheristic identification S. epidermidis isolate such as susceptibility test (antibiogram), could give indication of cluster spreading in certain area.
OBJECTIVES: Comparison between the susceptibility pattern of staphylococcus epidermidis in clinical specimen and environment in Atma Jaya Hospital.
METHODS: This study use cross sectional method. Description and analysis was done to bacteria culture data, whit the result of S. epidermidis, in 2014-2017, in Atma Jaya Hospital, including from the clinical samples and environment source. Analysis using WHONET 5.6 software and Unweighted Pair Group Method with Aritmeatic Mean (UPGMA).
RESULT: During four years, S. epidermidis that found in clinical samples are 11% (270/2451) and in environment are 26% (29/110). Resistance profile of S. epidermidis from clinical samples (n=270) shows 46 type of different profile while S. epidermidis isolated from environment (n=29) shows 14 type of profiles. The most resistance profile of S. epidermidis from clinical samples are 21% (57/270) isolate to 5 antibiotic Amoxicillin-Ampicillin-Cefradroxil-Cefepime-Cefixime. S. epidermidis profile from environment spread vary but the most (10%, 3/29) are to 2 antibiotics (Amoxicillin-Ampicillin). Six same resistance profile found in two groups. There are sameness resistance profile in 10.7% S. epidermidis isolate from clinical samples with isolates from environment that is to Amoxicillin-Ampicillin-Cefepime. Ten percent environment S. epidermidis isolate, have the same profile whit the clinical samples isolate that are resistance to Amoxicillin-Ampicillin. Relationship between isolates shows in dice coefficient of 0.85.
CONCLUSION: S. epidermidis from clinical samples and environment have the same resistance profile in less than 10% of isolates. There are indication of S. epidermidis cluster from clinical samples are from environment and or in reverse. Control of spreading S. epidermidis in normal flora or environment as the cause of infection become attention, especially in prevent infection program in Hospital.
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