Perioperative Statin Use: An Update  

Oleh:

Kalarickal, Phillip L. ; Fox, Charles J. ; Tsai, Jeffrey Y. ; Liu, Henry

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Anesthesiology Clinics (keterangan: ada di ClinicalKey) vol. 28 no. 04 (Dec. 2010), page 739-751.
Topik: ANESTHESIOLOGY; Statins; Perioperative cardiac complications; 3-hydroxyl 3-methylglutaryl coenzyme A reductase inhibitors; Inflammation

Ketersediaan

Perpustakaan FK Nomor Panggil: A34.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

HMG CoA reductase inhibitors (statins) are a proven modality to reduce serum cholesterol and have been shown to reduce morbidity and mortality in cardiovascular patients. Statins have also demonstrated improvements in postoperative outcomes among patients taking them in the perioperative period. Many of the studies are limited to select patient populations and/or select surgeries. This review will give an overview of the pharmacology of statins, summarize the mechanisms of the beneficial effects of statins, and provide an overview of evidence in the use of statins in the perioperative period.

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