Pengaruh Pemberian Jus jambu Biji (Psidium Guajava L) terhadap Volume Kaki dan Kadar Ion Nitrit Adjuvant Induced Arthritis Tikus Wistar  

Oleh:

Wiralis ; Purwaningsih, Endang

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI - non-atma jaya
Dalam koleksi: Media Medika Indonesiana vol. 43 no. 04 (Jan. 2009), halaman 188-196.
Topik: adjuvant arthritis; guajava; NO

Ketersediaan

Perpustakaan FK Nomor Panggil: M30.K.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Backgraund: Nitric oxide increases in adjuvant induced arthritis. It has been associated with the activities of nitrite oxide mediates inflammation and oxidant, it is a progressive joint disease. Characterized by swelling of the joint associated with an destruction of bone and cartilage. Jambu biji (Psidium Guajava L) is known to be the source of antioxidant and antiinflamation. Aim: To find out the difference volume joint and nitrite ion in adjuvant induced arthritis rats after administration of jambu biji (Psidium Guajava L) juice. Design and Method: An experimental study had been done using a randomized post test only control group. Twenty five Wistar rats were divided into 5 group. 2 control groups (K- and K +) and 3 treated groups (jambu biji juice 1 g/day, 2 g/day and 3 g/day). Volume joint to assay mercury placement pletismography Griess was used to assay nitrite ion (activity NO) serum. One Way Anova test and mann Withney test were appliedfor data analysis. Result: A significant difference in volume joint between the treated groups. A significant different nitrite ion was found among the treated groups (p<0.05). but not between the K + group and 2 g/day in 3 cc treated group. Conclusion: Jambu biji (Psidium Guajava L) juice shows an effect for volume joint and nitrite ion in consentration in adjuvant induced arthritis.

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