BACKGROUND: Candida albicans is a commensal fungus that lives in oral cavity, digestive system and genitourinary system. The incidence of resistance to antifungal treatment has been increasing. This study aims to evaluate the effect of Camellia sinensis on the growth of C. albicans.
METHODS: Dried leaves of C. sinensis obtained from Bogor Institute of Agriculture were extracted using aquades as the solvent. The methods used are disc diffusion and macrodilution. Experimental groups used the extract of four different concentration i.e 25 mg/mL, 12,5 mg/mL, 6,25 mg/mL and 3,125 mg/mL. The control groups consisted of positive control containing ketoconazole 1 mg/mL and negative control. RESULT: There was no inhibition zone observed in the disc diffusion method. In the macrodilution method there was no significant difference between the various concentrations of C. sinensis extract against the negative control.
CONCLUSION: Crude extracts of C. sinensis has no antifungal effect against the growth of C. albicans. |