Clinical Pharmacokinetics  

Oleh:

Atkinson, Arthur J., (Jr.)

Jenis: Article from Books - E-Book
Dalam koleksi: Principles of Clinical Pharmacology, page 11-23.
Fulltext: Clinical Pharmacokinetics.pdf (280.99KB)

Isi artikel

Pharmacokinetics is an important tool that is used in the conduct of both basic and applied research, and is an essential component of the drug development process. In addition, pharmacokinetics is a valuable adjunct for prescribing and evaluating drug therapy. For most clinical applications, pharmacokinetic analyses can be simplified by representing drug distribution within the body by a single compartment in which drug concentrations are uniform (1). Clinical application of pharmacokinetics usually entails relatively simple calculations, carried out in the context of what has been termed the target concentration strategy. We shall begin by discussing this strategy.

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