Detail Pengaruh Pemberian Abelmoschus esculentus L. (Moench) terhadap Jumlah Sel Sertoli Pada Testis Tikus Sprague Dawley Bibliografi Author: WINATA, FELICIA YUMITA ; Susanto, Karim (Advisor); Murtono, C (Examiner); Nurcahyanti, Agustina Dwi Retno (Ketua Sidang) Topik: Testis; NATURAL CONTRACEPTION; Okra; Decrease; Sertoli Cells; Sprague Dawley Rats; Penurunan; Sel Sertoli; Tikus Sprague Dawley Bahasa: (ID )     Penerbit: Fakultas Kedokteran Unika Atma Jaya     Tempat Terbit: Jakarta Utara    Tahun Terbit: 2016     Jenis: Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK) Fulltext: KTI Felicia Yumita Winata 2016060269.pdf (675.18KB; 26 download) Ketersediaan Perpustakaan FK Nomor Panggil: KTI-FK-1060 Non-tandon: tidak ada Tandon: 1  Lihat Detail Induk Abstract Background. 70-80% of the world's population use traditional medicine for their primary health care. Despite being widely used for their medicinal properties, A.esculentus (okra) could cause the degradation of testicular tissues if consumed for a long period of time. Objective. Quantitively count Sertoli cells number of Sprague Dawley rats to know the effects of administering okra to the testes. Method. This is an experimental research with analytical study. Okra pods was sun dried, finely crushed, then extracted. The extract was administered each day to Sprague Dawley rats which were divided to 4 groups of 7 rats: control group(1), dose of 250mg/kgBW(2), 500mg/kgBW(3), and 750mg/kgBW(4). By the end of 28 days, the testes were weighed and made to histological preparations. Total Sertoli cells number then counted. Results. The datas acquired show that with increasing dosage of okra, the total Sertoli count per testes automatically decreased. The mean numbers of Sertoli cells counted from group 1 to 4 are 27.94 x106 (±2.01 SEM), 21.62 x106 (±1.19 SEM), 15.90 x106 (±1.03 SEM), 9.90 x106 (±0.51 SEM) respectively. The reduced Sertoli cells count can be found even on the lowest given dose and on the highest dose the testicular tissues are visibly damaged thus the Sertoli cells are arduously counted. This experiment was proved meaningful with 95% confidence level (P < 0.05). Conclusion. Administering okra reduce Sertoli cells count of rats in reproductive age. The reduced Sertoli cells count affects the differentiation of germinal sperm cells and thus may lead to infertility. This anti-fertility trait of okra can be used as a form of a natural and reversible contraceptive method. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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