Detail Efektivitas Pemberian Dioscorea Esculenta Terhadap Penurunan Kadar Trigliserida Pada Tikus Hiperlipidemia Bibliografi Author: WULANSARI, JESSICA ; Margaret, Ayly (Advisor); Wibisono, Lies Kurniawati (Examiner) Topik: CARDIOVASCULAR DISEASES; HYPERLIPIDAEMIA; Dioscorea esculenta; triglycerides; diosgenin; water soluble fiber; trigliserida; diosgenin; serat pangan Bahasa: (ID )     Penerbit: Fakultas Kedokteran Unika Atma Jaya     Tempat Terbit: Jakarta Utara    Tahun Terbit: 2016     Jenis: Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK) Fulltext: KTI JESSICA WULANSARI.pdf (2.86MB; 86 download) Ketersediaan Perpustakaan FK Nomor Panggil: KTI-FK-995 Non-tandon: tidak ada Tandon: 1  Lihat Detail Induk Abstract BACKGROUND: Dyslipidemia or hyperlipidemia is one of the causes of various diseases, one of them is cardiovascular disease. Gembili (Dioscorea esculenta) is suspected to have effect on decreasing triglycerides level because it has a content of diosgenin and Water Soluble Polysaccharide. This study aims to determine the effectiveness of Dioscorea esculenta on decreasing triglycerides level in hyperlipidemic mice. METHODS: The study design used is experimental in vivo. Research carried out by pretest and posttest to 27 Sprague Dawley rats. Rats induced hyperlipidemia diet for 2 weeks and divided into 3 treatment groups ; negative control group (no treatment), positive control group (administration of simvastatin) and the intervention group (granting flour Dioscorea esculenta) and each are being intervented for 4 weeks. On day-42 1-2 drops sample of bloodwas taken from rats’ tails. Samplesdropped into the triglyceride measuring instrument “Multicare”. Data were collected and analyzed using Paired T Test. RESULTS: The results showed that the data were normally distributed (p> 0.05). In addition, decreased levels of triglycerides founded by giving Dioscorea esculenta flour for 4 weeksbut not significant (p > 0.05 and increased levels of triglycerides founded in the negative control group and positive control. CONCLUSION: This study shows that Dioscorea esculentahas a potention for lowering triglyceride levels despite the result was not significant. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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