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Hubungan Indeks Proliferasi KI-67 Dengan Positivitas Virus John Cunningham Pada Adenokasinoma Kolon
Bibliografi
Author:
SINDHUTOMO, JOPI CHANDRA
;
CYPRIANUS MURTONO
(Advisor);
Tjoa, Enty
(Examiner)
Topik:
COLON DISEASE
;
John Cunningham Virus
;
adenocarcinoma colon
;
proliferation index
;
Ki67
;
Virus John Cunningham
;
Adenokarsinoma Kolon
;
Indeks Proliferasi
Bahasa:
(ID )
Penerbit:
Fakultas Kedokteran Unika Atma Jaya
Tempat Terbit:
Jakarta Utara
Tahun Terbit:
2015
Jenis:
Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Fulltext:
KTI Jopi.pdf
(1.04MB;
3 download
)
Ketersediaan
Perpustakaan FK
Nomor Panggil:
KTI-FK-983
Non-tandon:
tidak ada
Tandon:
1
Lihat Detail Induk
Abstract
Background. There is so many controversy about the influence of John Cunningham Virus infection against clinicopathologic of colorectal cancer in patients. This study was conducted to prove the influence of John Cunningham Virus infection with index of cell cancer proliferation.
Objective. This research was conducted through the examination of cell proliferation activity by immunohistochemistry using primary antibody Ki-67. There are 12 samples of adenocarcinoma colon were fixed with formalin and then made paraffin blocks.
Result. This study measures the proliferation index Ki-67 in colorectal cancer with John Cunningham Virus either positive or negative. There are two positive samples infected with John Cunningham Virus and 10 samples negative. Index of cell proliferation in positive samples infected with John Cunningham Virus is 0% and 11%, while index of cell proliferation in the negative sample is 0% to 29%.
Conclusion. No significant association between colorectal cancer with John Cunningham Virus positive and colorectal cancer with John Cunningham Virus negative to index of cell proliferation Ki-67. Further research is needed to John Cunningham Virus infection and colorectal carcinogenesis.
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