Amantadine Resistant of Indonesia H5N1 Subtype Influenza Viruses During 2003-2008  

Oleh:

Dharmayanti, Ni Luh Putu Indi

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Microbiology Indonesia vol. 4 no. 1 (Apr. 2010), page 11-16.
Topik: Amantadine; Resistant; H5N1 subtype influenza virus
Fulltext: 3.pdf (1.05MB)

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: MM78 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The M2 protein of 146 avian influenza ( AI ) viruses data available in public database ( NCBI ), including 20 AI isolates used in this study, were sequenced at the M2 protein to find out the probability of mutation and the increase of resistance to amantadine after more than 5 year of their circulation in Indonesia. The result showed that during 2003-2008, around 62.58% ( 92/147 ) AI viruses in Indonesi have showed resistance to amantadine and 10 of them have dual mutations at V27A and S31N.

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