Background : The prevalence of Extended Spectrum Beta lactamase (ESBL)- producing bacteria continues to increase and has become a serious problem in the medical world, one of them is Escherichia coli. Therefore conducted a study that
aims to determine the prevalence of ESBL-producing Escherichia coli from clinical specimens sampled in the Laboratory of Microbiology, Faculty of Medicine, Atma Jaya Catholic University in 2014.
Methodology : This study is a descriptive study to show the prevalence of ESBLproducing Escherichia coli from the Laboratory of Microbiology, Faculty of Medicine, Atma Jaya Catholic University in 2014. The study was conducted in
January 2015 until March 2015 in the Laboratory of Microbiology, Faculty of Medicine, Atma Jaya Catholic University. ESBL identification consists of two stages:
screening test with disk diffusion method and ESBL confirmation test with doubledisk synergy test. In the screening test, antibiotic discs used are ceftazidime and
ceftriaxone. While the ESBL confirmation test, the discs used are amoxicillinclavulanate, ceftazidime and ceftriaxone. Both of these tests use the same medium, Mueller Hinton.
Results : Prevalence of ESBL-producing Escherichia coli is 21,42% (9/42). ESBLproducing Escherichia coli isolates derived from pus specimens (45%), urine specimens (33%), blood specimens (11%), and vaginal discharge specimens (11%).
Conclusions : The prevalence of ESBL-producing isolates of Escherichia coli in the Laboratory of Microbiology, Faculty of Medicine, Atma Jaya quite high (21.42%). ESBL-producing Escherichia coli isolates mostly came from pus and urine
specimens so that it becomes a major issue for further consideration by the clinician. |