Pengaruh Pemberian Ekstrak Purwoceng (Pimpinella alpina Molk) terhadap Peningkatan Indikator Vitalitas Pria  

Oleh:

Nasihun, Taufiqurrachman

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Sains Medika (Jurnal Kedokteran dan Kesehatan) vol. 01 no. 01 (Jan. 2009), page 53-62.
Topik: FSH; LH; TTe; Pimpinella alpina Molk; vitality

Ketersediaan

Perpustakaan FK Nomor Panggil: S11.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background. Pimpinella alpina Molk (PAM) or "purwoceng" has been traditionally used as an alternative treatment to enhance male vitality. Unfortunatelly, the effect of PAM to enhance vitallity which is indicated by increasing in consentration of Te, LH, and FSH has not been fully understood. This study was conducted to elucidate whether treatment of PAM crude extract will be able to enhance vitality which is indicated with increasing in level of testosteron, LH, and FSH. Design and Method: In the Post Test Control Group Design, 30 male of three month-old Sprague Dawley rats rondomly assigned into three groups, i.e Group A as a control, Group B, and group C was treated orally with aquadest 2 ml, 1 ml (25 mg), and 2 ml (50 mg) of PAM crude extract respectively for seven days. tetestosteron, LH, and FSH level were assessed by RIA and IRMA respectively. The different level of testosteron, LH, and FSH among the three groups was analyzed by ANOVA, followed by Post Hoct Tukey HSD. Result: The result showed significantly higher serum testosterone and LH level (p=0.049 and p=0.853 respectively) in 50 mg treated rats when compared with control while no significant difference was seen in the serum levels of these two markers between 25 mg treated rats and 50 mg treated rats. Statistical comparison revealed no significant difference in FSH level either in the two treated groups as compared to control or 25mg treated group to 25 mg treated group. Conclusion: Treatment of extract PAM 50 mg could enhance vitality which is indicated with increasing in testosterone and LH level, but had no effect to FSH level

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