Intraperitoneal Ropivacaine for Effective Pain Relief after Laparoscopic Appendectomy: a Prospective, Randomized, Double-blind, Placebo-controlled Study  

Oleh:

Kang, H. ; Kim, B-G

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Journal of International Medical Research vol. 38 no. 03 (May 2010), page 821-832.
Topik: ropivacaine; anaesthesia; pre-empitive analgesia; post-operative pain; appendectomy; laparoscopic surgery; intraperitoneal instillation

Ketersediaan

Perpustakaan FK Nomor Panggil: J11.K.2010.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

This prospective, randomized, double-blind, placebo-controlled study evaluated the effectiveness of intraperitoneal instillation of ropivacaine in the relief of pain in patients undergoing laparoscopic appendectomy. Patients in group C (placebo control group; n = 33) received normal saline and those in group I (instillation group; n = 30) received an instillation of 2 mg/kg ropivacaine at the initiation of the pneumoperitoneum. Visual analogue scale pain scores, fentanyl consumption and the frequency at which patients pushed the button (FPB) of a patient-controlled analgesia system during the post-operative period were significantly lower in group I compared with group C, and decreased gradually with time in both groups. The total amount of fentanyl consumed and the total FPB were significantly lower in group I compared with group C. Thus, intraperitoneal ropivacaine instillation reduced pain during the post-operative period after laparoscopic appendectomy. In addition, this drug was easy to administer and had no adverse effects at the dose used.

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