Association of adolescent obesity and lifetime nulliparity—The Study of Women's Health Across the Nation (SWAN)  

Oleh:

Polotsky, Alex J. ; Hailpern, Susan M. ; Skurnick, Joan H.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 93 no. 06 (Apr. 2010), page 2004-2011 .
Topik: Adolescents; body mass index; gravidity; obesity; parity

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2010.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective To evaluate whether adolescent obesity is associated with difficulties in becoming pregnant later in life. Design Cross-sectional analysis of baseline data from a longitudinal cohort. Setting Multiethnic, community-based observational study of U.S. women. Patient(s) Three thousand one hundred fifty-four midlife women. Main Outcome Measure(s) Lifetime nulliparity and lifetime nulligravidity. Result(s) Five hundred twenty-seven women (16.7%) women had never delivered a baby. Participants were categorized by self-reported high school body mass index (BMI): underweight (<18.5 kg/m2), normal (18.5–24.9 kg/m2), overweight (25–29.9 kg/m2), and obese (>30 kg/m2). The prevalence of lifetime nulliparity increased progressively across the high school BMI categories: 12.7%, 16.7%, 19.2%, and 30.9%, respectively. Multivariable logistic regression analysis confirmed that women who were obese adolescents had significantly higher odds of remaining childless compared with normal weight women (odds ratio [OR] 2.84; 95% confidence interval [CI], 1.59–5.10) after adjusting for adult BMI, history of nongestational amenorrhea, marital status, ethnicity, study site, and measures of socioeconomic status. Furthermore, adolescent obesity was associated with lifetime nulligravidity (OR = 3.93; 95% CI, 2.12–7.26). Conclusion(s) Adolescent obesity is associated with lifetime nulliparity and nulligravidity in midlife U.S. women.

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