Calculating cumulative live-birth rates from linked cycles of assisted reproductive technology (ART): data from the Massachusetts SART CORS  

Oleh:

Stern, Judy E. ; Brown, Morton B. ; Luke, Barbara

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 94 no. 04 (Sep. 2010), page 1334-1340.
Topik: Cumulative live-birth rate; live-birth rate per cycle; assisted reproductive technology; SART CORS

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2010.05 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective To determine the feasibility of linking assisted reproductive technology (ART) cycles for individual women to compare per-cycle and cumulative live-birth rates. Design Historical cohort study. Setting Clinic-based data. Patient(s) A total of 27,906 ART cycles with residency or treatment in Massachusetts during 2004–2006 and reported to the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System (SART CORS) on-line database. Intervention(s) None. Main Outcome Measure(s) Per-cycle and cumulative live-birth rates. Result(s) Linkage of cycles up to and including the first live-birth delivery revealed 14,265 women who averaged 1.9 ± 1.2 SD cycles (range 1–11). These cycles yielded 9,452 pregnancies resulting in 7,675 live-birth deliveries. From cycle 1 to cycle 4, the cumulative live-birth rate for all patients increased from 30.4% to 43.3%, 49.1%, and 51.9%, respectively, and plateaued thereafter at about 53%. The cumulative live-birth rate after three cycles using donor oocytes was ~60% for women aged <43 years and >50% for women =43 years; for autologous oocytes it was 60.1% for ages <35 years and declined steadily to 8.5% for ages =43 years. Conclusion(s) The results demonstrate the feasibility of linking ART cycles for individual women from SART CORS to characterize cumulative live-birth rates.

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