Detail Efektivitas Ekstrak Etil Asetat Daun Mimba terhadap Pertumbuhan Aspergillus flavus In Vitro Bibliografi Author: NICHELLE ; Margaret, Ayly (Advisor); Loanda, Evelyn (Advisor); Yolanda, Hanna (Examiner) Topik: HERBAL MEDICINE; A. flavus; neem; Azadirachta indica; antifungal; ethyl acetate; mimba; antifungal; etil asetat Bahasa: (ID )     Penerbit: Fakultas Kedokteran Unika Atma Jaya     Tempat Terbit: Jakarta Utara    Tahun Terbit: 2014     Jenis: Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK) Fulltext: Nichelle_KTI_2014.pdf (1.53MB; 0 download) Ketersediaan Perpustakaan FK Nomor Panggil: KTI-FK-726 Non-tandon: tidak ada Tandon: 1  Lihat Detail Induk Abstract BACKGROUND Aspergillus flavus (A. flavus) is an infectious agent of aspergillosis. Antifungal such as Amphotericin B and Itraconazole is reported have side effects. Neem or Azadirachta indica contains terpenoids which have antifungal effects and minimal side effects. Research of neem as aspergilosis drug is still limited.It stimulates the author to do a research in order to find out more about this . METHOD The study design was experimental in vitro. Neem leaves powder are obtained from Biochemistry Department, meanwhile A. flavus are obtained from Parasitology Department, School of medicine, Atma Jaya Catholic University of Indonesia. The used methods were disc diffusion and macrodilution. Experimental groups were divided in three concentrations i.e 0.5 g/dL, 1.0 g/dL, and 2.0g/dL. Control groups were consist of drug control (ketokonazole 0.1 g/dL), = negative, and positive control.Statistical analysis for disc diffusion used Kruskal Wallis test from software computer. RESULT Disc diffusion showed inhibition zone on concentration 2.0 g/dL. The three concentrations of ethyl acetate neem leaves extract showed significant differences statistically (p=0.04). Macrodilution test showed antifungal effect on concentration 1.0 g/dL. CONCLUSION Ethyl acetate neem leaves extract have antifungal effects on A. flavus growth in vitro. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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