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Prasugrel Sebagai Antiplatelet Golongan Penghambat Reseptor P2Y12 Dalam Strategi Terapi Sindrom Koroner Akut
Bibliografi
Author:
PITASARI, RIA
;
Harjanto, Bernardus Realino
(Advisor);
Tenggara, Riki
(Advisor);
Arieselia, Zita
(Examiner)
Topik:
CARDIOVASCULAR DISEASES
;
acute coronary syndrome
;
antiplatelet
;
clopidogrel
;
prasugrel
;
sindrom koroner akut
;
clopidogel
Bahasa:
(ID )
Penerbit:
Fakultas Kedokteran Unika Atma Jaya
Tempat Terbit:
Jakarta Utara
Tahun Terbit:
2014
Jenis:
Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Fulltext:
Ria_Pitasari_KTI_2014.pdf
(3.51MB;
4 download
)
Ketersediaan
Perpustakaan FK
Nomor Panggil:
KTI-FK-684
Non-tandon:
tidak ada
Tandon:
1
Lihat Detail Induk
Abstract
Acute Coronary Syndrome treatment paradigm has increased with a variety
of new research results, such as thienopyridine class of drugs (P2Y12 receptor
inhibitor) that works irreversibly as a platelet aggregation inhibitor. Recently, many
studies have been conducted on prasugrel, one of a class of drugs that is found to
have a more potent effect in reducing cardiovascular events. It mainly deals with
various limitation issues of clopidogrel. In some studies, prasugrel showed higher
inhibition of platelet aggregation ability that it reduces ischemic events in
Percutaneuos Coronary Intervention (PCI) treatment in the case of Acute Coronary
Syndrome. However, the side effect of bleeding is found to increase significantly and
it becomes the focus of the use of prasugrel problem. This literature study will
discuss some studies that disclose the efficacies and limitations of prasugrel.
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