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Use of OM-85 BV for the Prevention of Acute Respiratory Tract Infections in Occupational Medicine
Oleh:
Carmona-Ramirez, MA
;
Alvarez-Gomez, V
;
Berber, A
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
The Journal of International Medical Research vol. 30 no. 03 (May 2002)
,
page 325-329.
Topik:
OM-85 BV
;
immunostimulatory agent
;
acute respiratory tract infections
;
occupational medicine
;
manufacturing workers
;
incidence
Ketersediaan
Perpustakaan FK
Nomor Panggil:
J11.K
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
This study evaluated the safety and efficacy of the immunostimulatory agent OM-85 BV in 112 male car-factory workers who were highly susceptible to acute respiratorytract infections (ARTIs), each having experienced ¡Ý 4 ARTIs during 1999. From January to March 2000, each worker received one capsule of OM-85 BV (7 mg) per day for 10 consecutive days each month. The patients were followed for a further 9 months. Mean number of ARTIs decreased from 8.2 ¡À 2.1 per worker in 1999 to 5.3 ¡À 2.9 in 2000; i.e. a difference of ¨C2.9 (95% confidence intervals, ¨C3.5 to ¨C2.4). Similar effects were observed in men who had different job roles, and no adverse events were reported during drug administration. We concluded that OM-85 BV appears to be safe and effective in reducing the incidence of ARTIs in susceptible workers, although further double-blind, placebo-controlled clinical trials are required.
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