Detail The expression of mitochondrial heat shock protein 10 in oral lesions with HPV positive (Folia Medica Indonesiana Vol. 45 No. 2 April - June 2009) Bibliografi Author: Prayitno, Adi ; Asmara, Widya ; Mudigdo, Ambar ; Rukmo, Mandojo ; Putra, Suhartono Taat Topik: Stress Cells; HPV; Heat Shock Proteins 10; Apoptosis; Psychoneuroimmunology Bahasa: (EN )     Penerbit: Fakultas Kedokteran Universitas Airlangga     Tempat Terbit: Surabaya    Tahun Terbit: 2009     Jenis: Article - diterbitkan di jurnal ilmiah nasional Fulltext: EXPRESSION OF MITOCHONDRIAL HEAT SHOCK PROTEIN.pdf (291.48KB; 1 download) [Informasi yang berkaitan dengan koleksi ini di internet] Abstract Hundreds of studies over the last 25 years have shown that stress contributes to many illnesses includingcardiovascular disease, endocrine disease and cancer. Persistent infection with human papilloma-virus may play acentral role in cervical carcinogenesis. Cancer may be defined as uncontrolled tissue growth in susceptible patient,with result from imbalance between cell division and program cell death (apoptosis). Psychosocial factors mayinfluence cervical carcinogenesis via a psychoneuroimmunology pathway. Head and neck squamous cell carcinoma(HNSCC) is the 6th most common cancer worldwide. Alcohol/tobacco consumption is the most important risk factor forthis neoplasia; nevertheless, since 1983 it has been suggested that human papilloma viruses (HPV) have a role inHNSCC. The aim of this study is to know the protein expression especially heat shock protein 10 in oral lesions withHPV positive. Seventeen samples from many kind oral cavity lesions were collected from 1 January 2007 to 1November 2007. DNA isolation and diagnose related HPV infections are made by Henk Schmits and/or Nigel McMillanand Nina Fowler method with some modifications. Protein isolation was doing with Vincent and Philippe method withsome modifications and the SDS-PAGE protein electrophoresis was doing with 30mA for 6 hour. The result of thisexperiment was seen the band as 10kDa protein. And the conclusion is the expression oh heat shock protein 10 was upregulated in oral lesion with HPV positive. Certainly the apoptosis process was on Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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