Absence of chlamydial deoxyribonucleic acid from testicular and epididymal samples from men with obstructive azoospermia  

Oleh:

Sripada, Sreebala ; Amezaga, Maria Rosario ; Hamilton, Mark ; McKenzie, Hamish ; Templeton, Allan ; Bhattacharya, Siladitya

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 93 no. 03 (Feb. 2010), page 833-836.
Topik: Chlamydia; male infertility; azoospermia

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2010.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To identify Chlamydia trachomatis DNA by polymerase chain reaction in the upper genital tract of men with obstructive azoospermia compared with men seeking vasectomy reversal. Design Case–control study. Setting Tertiary referral center, Aberdeen Royal Infirmary, Aberdeen, United Kingdom. Patient(s) Cases were men with idiopathic obstructive azoospermia, and controls were men with azoospermia secondary to vasectomy. Intervention(s) Chlamydia trachomatis–specific DNA test by polymerase chain reaction on testicular and epididymal biopsy samples, as well as epididymal aspirate. Main Outcome Measure(s) Presence of Chlamydia trachomatis DNA. Result(s) We did not detect the presence of Chlamydia trachomatis–specific DNA by polymerase chain reaction in the epididymis or testis of 36 asymptomatic men with obstructive azoospermia (14 cases, 22 controls). Conclusion(s) Our hypothesis that unrecognized, asymptomatic chlamydial infection will lead to complete bilateral obstruction of the male genital tract remains unproven.

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