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ArtikelIgA Antiphospholipid Antibodies in HTLV-1-Associated Tropical Spastic Paraparesis  
Oleh: Wilson, Wendell A ; Morgan, Owen St. C ; Barton, EN ; Smikle, M ; Handchard, B ; Blattner, WA ; Doggett, Sarah ; Gharavi, Azzudin E
Jenis: Article from Journal
Dalam koleksi: Lupus vol. 4 no. 2 (1995), page 138-141.
Topik: Phospholipid Antibodies; Tropical Spastic Paraparesis
Fulltext: 138.full.pdf (342.62KB)
Isi artikelA retrovirus, human T cell lymphotropic virus type 1 (HTLV-1), is an essential but not a sufficient aetiologic factor for tropical spastic paraparesis (TSP). Because some TSP patients have biological false positive tests for treponemal infections (BFP-STS), we used ELISA to study BFP-STS and anticardiolipin antibodies in 42 Jamaican TSP patients. The data indicate that in TSP anticardiolipin antibodies occur in about 26% of patients, are associated with biological false positive treponemal serology, are relatively restricted to the IgA isotype and may be induced by HTLV-1 or other nontreponemal infections.
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