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ArtikelThe role of B2-Glycoprotein I in The Antiphospholipid Syndrome  
Oleh: Krilis, SA ; Sheng, YH ; Kandiah, DA
Jenis: Article from Journal
Dalam koleksi: Lupus vol. 5 no. 2 (1996), page 151-152.
Topik: Antiphospholipid Syndrome; Antiphospholipid Antibodies; B2-Glycoprotein
Fulltext: 150.full.pdf (326.96KB)
Isi artikelAntiphospholipid antibodies were originally thought to bind negatively-charged (aniomic) phospholipids. Current evidence suggests that the target antigen is considerably more complex and includes B2-glycoptrotein I, a phospholipid-binding plasma protein. Our understanding of the pathophysiology of the antiphospholipid syndrome has increased exponentially with a number of studies into the interactions of antiphospholipid antibodies and B2-glycoptrotein I.
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