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The role of B2-Glycoprotein I in The Antiphospholipid Syndrome
Oleh:
Krilis, SA
;
Sheng, YH
;
Kandiah, DA
Jenis:
Article from Journal
Dalam koleksi:
Lupus vol. 5 no. 2 (1996)
,
page 151-152.
Topik:
Antiphospholipid Syndrome
;
Antiphospholipid Antibodies
;
B2-Glycoprotein
Fulltext:
150.full.pdf
(326.96KB)
Isi artikel
Antiphospholipid antibodies were originally thought to bind negatively-charged (aniomic) phospholipids. Current evidence suggests that the target antigen is considerably more complex and includes B2-glycoptrotein I, a phospholipid-binding plasma protein. Our understanding of the pathophysiology of the antiphospholipid syndrome has increased exponentially with a number of studies into the interactions of antiphospholipid antibodies and B2-glycoptrotein I.
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