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Predictive value of embryo grading for embryos with known outcomes
Oleh:
Weitzman, Vanessa N.
;
Schnee-Riesz, Jennifer
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 93 no. 02 (Jan. 2010)
,
page 658-662.
Topik:
REPRODUCTIVE HEALTH
Ketersediaan
Perpustakaan FK
Nomor Panggil:
F02.K.2010.01
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Objective To compare pronuclear morphology (Z-score), day 3 embryo grade, and day 3 cell number in the prediction of successful implantation rates (IRs), including cycles in which all or none of the embryos implanted. Design Retrospective analysis. Setting University-based IVF center. Patient(s) Four hundred twenty-six fresh IVF day 3 transfers of 852 embryos in women <36 years of age from January 2000 to December 2003 in whom all or none of the embryos implanted. Main Outcome Measure(s) Evaluation of Z-scores, embryo morphology, cell number, and IR. Result(s) Day 3 parameters were more predictive than Z-scores. When early parameters were poor (Z-score) but late parameters were both good, the IR was 38%, compared with 4% when the Z-score was good but the late parameters were poor. Conclusion(s) Embryo grading systems are useful in the prediction of embryo implantation. In particular, cell number and embryo grade are more predictive than Z-scores. Therefore, late parameters have a better prognostic value than Z-scores when selecting embryos for transfer.
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