Hematopoietic Stem Cell Transplantation for Hemoglobinopathies: Current Practice and Emerging Trends  

Oleh:

Smiers, Frans J. ; Krishnamurti, Lakshmanan ; Lucarelli, Guido

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 57 no. 01 (Feb. 2010), page 181-205.
Topik: Hematopoietic stem cell transplantation; HSCT; Hemoglobinopathies

Ketersediaan

Perpustakaan FK Nomor Panggil: P13.K.2010.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Despite improvements in the management of thalassemia major and sickle cell disease, treatment complications are frequent and life expectancy remains diminished for these patients. Hematopoietic stem cell transplantation (HSCT) is the only curative option currently available. Existing results for HSCT in patients with hemoglobinopathy are excellent and still improving. New conditioning regimens are being used to reduce treatment-related toxicity and new donor pools accessed to increase the number of patients who can undergo HSCT.

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