Hematopoietic Stem Cell Transplantation for Osteopetrosis  

Oleh:

Steward, Colin G.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 57 no. 01 (Feb. 2010), page 171-180 .
Topik: Osteopetrosis; Hematopoietic transplant; Hypocalcemia; Pulmonary hypertension

Ketersediaan

Perpustakaan FK Nomor Panggil: P13.K.2010.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Osteopetrosis is the generic name for a group of diseases caused by deficient formation or function of osteoclasts, inherited in either autosomal recessive or dominant fashion. Osteopetrosis varies in severity from a disease that may kill infants to an incidental radiological finding in adults. It is increasingly clear that prognosis is governed by which gene is affected, making detailed elucidation of the cause of the disease a critical component of optimal care, including the decision on whether hematopoietic stem cell transplantation is appropriate. This article reviews the characteristics and management of osteopetrosis.

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