Effects of variations in serum estradiol concentrations on secretory endometrial development and function in experimentally induced cycles in normal women  

Oleh:

Groll, Jeremy M ; Usadi, Rebecca S. ; Lessey, Bruce A. ; Lininger, Ruth A. ; Young, Steven L. ; Fritz, Marc A.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 92 no. 06 (Dec. 2009), page 2058-2061.
Topik: Endometrium; receptivity; estrogen; luteal phase; beta-3 integrin; osteopontin

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2009.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Eighteen normal women underwent pituitary down-regulation with leuprolide, followed by a 10-day treatment with 0.2 mg/d transdermal estradiol (E2) with subsequent allocation to one of two 10-day estradiol regimens plus 40 mg daily intramuscular P: supraphysiologic (0.2 mg/d transdermal E2 mg/d vaginal micronized E2) or subphysiologic (no exogenous E2 treatment). Average E2 and P in the supraphysiologic, physiologic, and subphysiologic groups were 1,175.9 pg/mL and 17.5 ng/mL, 136.9 pg/mL and 21.2 pg/mL, and 23.8 ng/mL and 22.0 ng/mL, respectively, and there were no differences between groups in endometrial histology or expression of biomarkers of receptivity.

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