Chronic endometritis is a frequent finding in women with recurrent implantation failure after in vitro fertilization  

Oleh:

Johnston-MacAnanny, Erika B. ; Hartnett, Janice ; Engmann, Lawrence L.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 93 no. 02 (Jan. 2010), page 437-441.
Topik: OBSTETRI GINEKOLOGI; In vitro fertilization; chronic endometritis; recurrent implantation failure; endometrial biopsy

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2010.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To determine the role of endometrial sampling for identification and treatment of chronic endometritis (CE) in patients undergoing IVF-ET who repeatedly failed to conceive despite the transfer of good-quality embryos. Design Retrospective chart review. Setting University-based tertiary fertility center. Patient(s) Thirty-three patients with recurrent implantation failure (RIF) who underwent endometrial sampling and subsequent ET were analyzed based on immunohistochemically confirmed CE: CE present on biopsy (group 1; n = 10) and CE absent on biopsy (group 2; n = 23). Patients with RIF undergoing IVF cycles during the same time period who did not have endometrial sampling were used as controls (group 3; n = 485). Intervention(s) Endometrial sampling for CE and subsequent antibiotic treatment in affected patients followed by another IVF-ET cycle. Result(s) Chronic endometritis was identified in 30.3% of patients with RIF. Group 1 had lower implantation rates (11.5%) in the IVF cycle following treatment than did group 2 and group 3 (32.7% and 20.3%, respectively). Clinical pregnancy and ongoing pregnancy rates were similar across groups. Conclusion(s) Recurrent implantation failure warrants investigation of CE as a contributing factor. Women demonstrating CE on endometrial sampling have lower implantation rates in a subsequent IVF-ET cycle; however, there were no differences in subsequent clinical pregnancy or ongoing pregnancy rates after successful antibiotic treatment.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali