Detail The Expression of Prolactin and Oxytocin Genes in Lactating BALB/C Mice Supplemented with Mature Sauropus androgynus Leaf Extracts (di dalam Prosiding International Conference on Food Engineering and Biotechnology IPCBEE vol.9 2011) Bibliografi Author: Soka, Susan ; Wiludjaja, Jessica ; MARCELLA Topik: Sauropus androgynus; prolactin; oxytocin; qRT-PCR; papaverine Bahasa: (EN )    ISBN: 2010-4618(ISSN)     Penerbit: International Association of Computer Science and Information Technology Press (IACSIT)     Tempat Terbit: Bangkok, Thailand    Tahun Terbit: 2011     Jenis: Papers/Makalah - pada seminar internasional Fulltext: Expression of Prolactin and Oxytocin Genes - with Sauropus androgynus - Susan Soka - optim.pdf (673.07KB; 2 download) [Informasi yang berkaitan dengan koleksi ini di internet] Abstract Breastfeeding is a natural way of providing young infants with the nutrients that they need for healthy growth and development. Breast milk is the best form of nutrition for infants before they are able to eat and digest other foods. Sauropus androgynus is believed to increase breast milk production during lactation and is traditionally consumed by Indonesians. A total of 24 lactating Mus musculus strain BALB/c were divided into three groups of eight. During the lactation period, they were given different dosage treatments for 12 days. The first and second groups received a dosage of mature S. androgynus leaf extracts 173.6 mg/kg and 868 mg/kg mice body weight, respectively. The third group, as the control group, did not receive any mature S. androgynus leaf extracts. The expression of oxytocin gene in the lactating mice supplemented with 173.6 mg/kg and 868 mg/kg mice body weight mature S. androgynus leaf extracts increased significantly by 22.02-fold and 46.39-fold, respectively compared to the control group (p < 0.05, ANOVA). The prolactin gene expression level in the mice group which were supplemented with 173.6 mg/kg mice body weight mature S. androgynus leaf extracts increased significantly 14.65-fold compared to the controlled ones, whereas the second group which were supplemented 868 mg/kg increased significantly 2.42-fold compared with the controlled ones (p < 0.05, ANOVA). The increased gene expression in both treatments could be related to papaverine content in mature S. androgynus leaves that relaxed the smooth muscles and dilated the blood vessels. This also caused a smoother circulation of oxytocin hormone through the bloodstream. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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