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ArtikelAutistic features in girls from a psychiatric sample are strongly associated with a low 2D:4D ratio  
Oleh: De Bruin, Esther I. ; De Nijs, Pieter F.A.
Jenis: Article from Bulletin/Magazine - ilmiah internasional
Dalam koleksi: Autism vol. 13 no. 05 (Sep. 2009), page 511–521.
Topik: autism; diagnosis; digit ratio
Fulltext: 511.pdf (123.17KB)
Isi artikelAutistic features such as deficits in social interactions and communication have been associated with a low 2D:4D ratio in normal children.This study assessed this association in a large sample of children with a variety of psychiatric disorders (n = 35 girls and n = 147 boys). Autistic features were assessed with a highly valid and reliable measure (Autism Diagnostic Observation Schedule–Generic). Correlations between the 2D:4D ratio and autistic features were computed separately for boys and girls. Some small negative correlations (r = –0.17 and r = –0.19) were found in the right hand for boys; however, particularly in girls, large negative correlations (r = –0.51 to r = –0.64) were found in the left hand. A low 2D:4D ratio in girls was highly predictive of the presence of autistic features. Thus, a low ratio could possibly be used as a diagnostic predictor in clinical practice.
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