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Trend of Antibiotics Susceptibility of Multidrugs Resistance Pseudomonas Aeruginosa in Jakarta and Surrounding Areas From 2004 to 2010 (dalam African Journal of Microbiology Research - AJMR Vol. 6, 9 March, 2012)
Bibliografi
Author:
Moehario, Lucky Hartati
;
Hartono, Teguh S.
;
Wardoyo, E. Hagni
;
Tjoa, Enty
Topik:
Gram Negative Bacteria
;
P. aeruginosa
;
Antibiotic Susceptibility.
Bahasa:
(EN )
Penerbit:
Academic Journals Inc.
Tempat Terbit:
Lagos
Tahun Terbit:
2012
Jenis:
Article - diterbitkan di jurnal ilmiah internasional
Fulltext:
Lucky H. Moehario; Teguh S. Hartono; E. Hagni Wardoyo dan Enty Tjoa.pdf
(833.57KB;
4 download
)
Abstract
Pseudomonas aeruginosa is an opportunistic Gram negative microorganism, usually related to serious infections within hospital environment and causes significant increase in patient’s morbidity and mortality. This study aimed to report antibiotic susceptibility of P. aeruginosa originated from all kind of specimens received at Clinical Microbiology Laboratory of the Faculty of Medicine, University of Indonesia, Jakarta, from 2004 to 2010, and evaluate their trend of susceptibility to certain antibiotics. Culture and identification of specimens were performed according to standard microbiology procedures. Antibiotic susceptibility tests were carried out according to performance standards for antimicrobial susceptibility testing from the Clinical and Laboratory Standards Institute. The data was processed using WHO-NET Version 5.6 program. P. aeruginosa was constantly found between 12 to 19% among other Gram negative bacteria. A significant decrease of susceptibility against ceftazidim, cefepime, cefoperazone, gentamicin, amikacin, tobramycin, ciprofloxacin, levofloxacin, meropenem and imipenem was observed. Susceptibility to aztreonam and piperacilline-tazobactam was decreased, though it was not statistically significant. In 2010, among the anti-pseudomonas antibiotics, imipenem showed good activity (80%). Overall, declining trend of susceptibility to all antibiotic tested was significantly observed. Imipenem was found to be the only anti-pseudomonas antibiotic with good activity (80%).
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