Electronic Screening Improves Efficiency in Clinical Trial Recruitment  

Oleh:

Thadani, Samir R ; Chunhua, Weng ; Bigger, J. Thomas ; Ennever, John F. ; Wajngurt, David

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: JAMIA ( Journal Of the American Medical Informatics Association ) vol. 16 no. 6 (Nov. 2009), page 869-873.
Topik: E-screening

Ketersediaan

Perpustakaan FK Nomor Panggil: J43.K.2009.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

This study evaluated the performance of an electronic screening (E-screening) method and used it to recruit patients for the NIH sponsored ACCORD trial. Out of the 193 E-screened patients, 125 met the age criterion (“age = 40”). For all of these 125 patients, the performance of E-screening was compared with investigator review. E-screening achieved a negative predictive accuracy of 100% (95% CI: 98–100%), a positive predictive accuracy of 13% (95% CI: 6–13%), a sensitivity of 100% (95% CI: 45–100%), and a specificity of 84% (95% CI: 82–84%). The method maximized the use of a patient database query (i.e., excluded ineligible patients with a 100% accuracy and automatically assembled patient information to facilitate manual review of only patients who were classified as “potentially eligible” by E-screening) and significantly reduced the screening burden associated with the ACCORD trial.

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