Psychoeducational profile of the 22q11.2 microdeletion: A complex pattern  

Oleh:

Moss, Edward M. ; Batshaw, Mark L. ; Solot, Cynthia B. ; Gerdes, Marsha ; McDonald-McGinn, Donna M.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Journal of Pediatrics vol. 135 no. 02 (Feb. 1999), page 193-198.
Topik: ADHD ; Attention deficit hyperactivity disorder; CELF-R ; Clinical Evaluation of Language Fundamentals - Revised; NVLD ; Nonverbal learning disability; WISC-III ; Wechsler Intelligence Scale for Children - Third edition

Ketersediaan

Perpustakaan FK Nomor Panggil: J45.K.1999.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Objectives: To examine the psychoeducational profile associated with the chromosome 22q11.2 microdeletion (DiGeorge/velocardiofacial syndrome). Study design: Thirty-three patients (aged 6 to 27 years) with a 22q11.2 microdeletion underwent psychoeducational testing as part of a comprehensive evaluation. Nonparametric statistics were used to compare verbal and performance IQ, academic achievement scores, and receptive versus expressive language scores. Post hoc comparisons were made of IQ subtest scores and of language versus verbal IQ. Results: Full-scale IQ ranged from the normal to the moderately retarded range. Mean verbal IQ was significantly higher than mean performance IQ. In a similar manner, mean reading and spelling scores were superior to the mean mathematics score, although achievement scores typically were in the range of verbal IQ. In addition, many children showed clinically significant language impairments, with mean language scores lower than mean verbal IQ. Conclusions: The IQ and academic profiles are reminiscent of a “nonverbal learning disability,” although achievement was not discrepant from IQ. The coincidence of language impairment with a relative strength in reading belies a unique neuropsychologic profile. Educational programming for these children must address both verbal and nonverbal deficits.

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