Peranan enzyme-linked immunosorbent assay (ELISA) dalam diagnosis Pemfigus  

Oleh:

Lembar, Stefanus ; Chandra, Aji Bayu

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI - atma jaya
Dalam koleksi: Majalah Kedokteran Damianus vol. 08 no. 03 (Sep. 2009), page 168-176.
Topik: Pemphigus Vulgaris and Foliaceus; Anti-Desmoglein 1 and 3; ELISA
Fulltext: D01 v8 n3 p168 kelik2023.pdf (4.86MB)

Ketersediaan

Perpustakaan PKPM Nomor Panggil: M61 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada	Lihat Detail Induk
Perpustakaan FK Nomor Panggil: D01.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada	Lihat Detail Induk

Isi artikel

Pemphigus is an auto-immune disease, characterized by bullous formation on the skin. The antibody is directed against keratinocyte component, desmoglein (Dsg) 1 and 3. Pemphigus vulgaris (PV) and foliaceus (PF) are the most frequent type. Anti-Dsg 1 is the major antibody in PF, meanwhile anti-Dsg 3 is the major antibody found in PV. There are two subtypes in PV, which are mucosal type and musosutaneus type. The clinical manifestation in PV is determined by the antibody profile. Finding the antibody is the gold standard for diagnosis for decades, but now Enzyme-Linked Immunosorbent Assay ELISA is getting more attention for diagnosis of pemphigus, because its ability to differ the antibody profile, thus the subtypes of pemphigus can be differentiated, and also its positive correlation with the clinical course, that can be used to determine the treatment management.

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